Where is dukoral available

Skip directly to site content Skip directly to page options Skip directly to A-Z link. Cholera - Vibrio cholerae infection. Section Navigation. Facebook Twitter LinkedIn Syndicate. Minus Related Pages. Please check and try again Please enter recipient's email Recipient's email is invalid. Please check and try again Agree to Terms required. Thank you for sharing our content. A message has been sent to your recipient's email address with a link to the content webpage. Your name: is required Error: This is required.

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Download leaflet Reporting side effects Data sources Disclaimer What it is used for Cholera caused by serogroup 01 Vibrio cholerae: Active immunisation of adults and children from two years of age, who will be visiting areas epidemic or endemic for cholera and who are at high risk of infection.

How to take it This medicine is a pack that contains more than one part. The three main studies involved a total of almost , people. In all three studies, Dukoral, given as either two or three doses, was compared with placebo a dummy vaccine. The studies took place in areas where cholera is found. The first study involved over 89, people in Bangladesh and compared Dukoral with the same vaccine without the toxin and with placebo.

In this study, Dukoral was made using cholera toxin extracted from cholera bacteria in place of the newer recombinant toxin. The other two studies compared Dukoral containing recombinant cholera toxin with placebo in over 22, people in Peru. The people in the final study also received a booster dose 10 to 12 months later. A further study was carried out to show that Dukoral could produce antibodies in people who do not come from areas where cholera is found.

The length of protection was different for adults and children, lasting for six months in children and for two years in adults. In adults, two vaccine doses were shown to be as effective as three.

Side effects with Dukoral are not common. However, the following side effects are seen in between 1 and 10 patients in 1, headache, diarrhoea, and abdominal tummy pain, cramps, gurgling gas or discomfort. For the full list of side effects reported with Dukoral, see the package leaflet. Dukoral should not be used in people who may be hypersensitive allergic to any of the active substances , to any of the other ingredients or to formaldehyde. Its use should be postponed in patients with a short-lived illness affecting the stomach or gut, or with a fever.

The CHMP noted that the risk of cholera for regular tourists is minor, but that Dukoral could be important for certain groups, such as healthcare workers in cholera epidemics. The European Commission granted a marketing authorisation valid throughout the European Union for Dukoral on 28 April All rights reserved. The University of Minnesota is an equal opportunity educator and employer. Skip to main content. University of Minnesota.

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